PCOS Favourites Bundle
- Significantly reduces testosterone levels
- Reduces insulin resistance
- Improves natural ovulation rates
- Reduces inflammation levels
In the PCOS favourites bundle we have paired together our 3 most popular capsule supplements all in one bundle; Spearmint tea, NAC, and berberine. This combination can help to improve a range of PCOS symptoms from hirsutism, weight gain, hair loss, and irregular menstrual cycles.
N-acetyl-cysteine (NAC) is the acylated form of L-cysteine amino acid and also one of the precursors of glutathione, an antioxidant substance. Cysteine is a semi-essential amino acid. It’s considered semi-essential because your body can produce it from other amino acids, namely methionine, and serine. It becomes essential only when the dietary intake of methionine and serine is low. Cysteine is found in most high-protein foods, such as chicken, turkey, yogurt, cheese, eggs, sunflower seeds, and legumes. N-acetyl cysteine (NAC) is a supplement form of cysteine.
Researchers investigated the effects of NAC administration for 5-6 weeks on insulin-associated parameters in obese and lean women. They determined a significant decrease in testosterone and androgen levels. In addition, increased peripheral insulin sensitivity appeared in women with PCOS.
Thus, both metformin and NAC have important effects on hyperandrogenism, hyperinsulinemia, and menstrual cyclicity in women with PCOS.
Spearmint is a type of mint that originally was found in Asia and Europe. It’s often used to flavour foods, mouthwash, toothpaste, and chewing gum but, did you know that brewed as a tea, spearmint has some potentially wonderful benefits for those with PCOS.
One study found that drinking two cups of spearmint tea had significant anti-androgen effects for women with PCOS. For the women who participated in the study, Free and total testosterone levels were significantly reduced, LH and FSH also increased. The women’s subjective (self-assessed) assessments of their degree of hirsutism were significantly reduced in the spearmint tea group. Other studies have also found that spearmint tea may also help to improve follicular development and ovulation.
Interestingly as well, a study looking into the combination of spearmint tea and flaxseeds found that this combination may help at reducing testosterone levels, increasing progesterone levels, and improving follicle counts in the ovary. Although more research is needed to definitely find the benefits and underlying mechanisms, spearmint tea is generally quite a safe and relatively cheap drink that is easy to incorporate into your daily life, it’s also caffeine and calorie-free.
It's also interesting because although the total amount of research behind it is quite small compared to other supplements, the overall feedback I see from customers is probably one of the most positive out of everything.
Berberine is a compound in several plants, including goldenseal, barberry, Oregon grape, and tree turmeric that has been a part of Chinese and Ayurvedic medicine for thousands of years. Many studies of berberine have indicated that it can treat several metabolic health conditions, including diabetes, obesity, and heart problems.
A clinical trial compared metformin use and NAC over a 24-week period. Both groups had equal results in terms of decreased BMI and free testosterone levels, improved insulin sensitivity, menstrual cyclicity, and lower hirsutism scores
Other known benefits of NAC include:
- NAC is needed to make and replenish glutathione, one of the body’s most important antioxidants, which helps neutralize free radicals that can damage cells and tissues in your body.
- By helping replenish the antioxidant glutathione and regulate glutamate, NAC helps promote optimal brain health
- Improve insulin sensitivity and reduce inflammation in fat cells.
- Induced a redistribution of adipose tissue(body fat), reducing VAT (mid-section fat) even in the absence of weight loss.
- Improved insulin sensitivity, quite like metformin
- Improved ovulation rates per cycle
- Is effective on fertility and live birth rates
- Supplementation showed few side effects
A 2020 systematic review (PMC7028834) titled "Polycystic ovary syndrome management: a review of the possible amazing role of berberine" in PCOS treatment of over 1,000 PCOS women found that Berberine:
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